Through a constitutional amendment, acts of parliament, and a referendum in 2018, the then president, Nana Addo Dankwa Akufo-Addo, increased the number of administrative regions in Ghana from ten (10) to sixteen (16). The six new regions that were added were all created from existing regions by dividing them up into two or three parts.

The tben Brong-Ahafo Region was divided into three regions with the new regions designated as Bono Region, Bono East Region, and Ahafo Region.

The then Northern Region was divided into three regions with the new regions designated as Northern Region, North East Region, and Savannah Region.

The then Volta Region was divided into two with the new regions designated Volta Region and Oti Region.

The then Western Region was divided into two with the new regions designated Western Region and Western North Region.

Below are the 16 administrative regions of Ghana, arranged in alphabetical order, with their capitals and regional ministers.

No. Region Capital Regional Minister
1 Ahafo Goaso Charity Gardiner
2 Ashanti Kumasi Dr. Frank Amoakohene
3 Bono Sunyani Joseph Addae Akwaboah
4 Bono East Techiman Francis Owusu Antwi
5 Central Cape Coast Eduamoah Ekow Panyin Okyere
6 Eastern Koforidua Rita Akosua Adjei Awatey
7 Greater Accra Accra Linda Obenewaa Akweley Ocloo
8 Northern Tamale Ali Adolf John
9 North East Nalerigu Ibrahim Tia
10 Oti Dambai John Kwadwo Gyapong
11 Savannah Damongo Salisu Be‑Awuribe
12 Upper East Bolgatanga Akamugri Donatus Atanga
13 Upper West Wa Puozuing Charles Lwanga
14 Volta Ho James Gunu
15 Western Sekondi‑Takoradi Joseph Nelson
16 Western North Sefwi Wiawso Wilbert Petty Brentum